Author

B. Drew

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Open access Oct 2026

Genetic and Pharmacological Targeting of Hsp72 Overexpression/Induction in an Alzheimer's Disease Mouse Model With Combined Amyloid and Tau Pathology.

Heat shock protein 72 (Hsp72), a stress-inducible member of the Hsp70 family, has been implicated in mitigating the pathogenic effects of amyloid-beta (Aβ) and tau pathology; both key factors associated with the development and progression of Alzheimer's disease (AD). However, no in vivo study has been conducted to inv...

J. P. Marshall, A. Harutyunyan, J. Ng et al. · Journal of Neuroscience Rese... · 0 citations

Open access Aug 2026

The Drp1 inhibitor DRP1i2 confers cardioprotection against doxorubicin-induced cardiotoxicity

Anthracyclines such as doxorubicin are highly effective chemotherapeutic agents, but their clinical use is limited by dose-dependent cardiotoxicity associated with mitochondrial dysfunction. Dysregulated mitochondrial dynamics, particularly excessive dynamin-related protein 1 (Drp1)-mediated fission, has been implica...

Yali Deng, S. Bass-Stringer, S. Bond et al. · Cell Death Discovery · 0 citations