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B. D'Onofrio

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Open access Sep 2026

Major adverse cardiac events and mortality associated with ADHD and its treatment in adults with type 2 diabetes: a multi-national cohort study

Attention-deficit/hyperactivity disorder (ADHD) has been linked to elevated risk of type 2 diabetes (T2D). However, the impact of ADHD and ADHD medication use on prognosis and health outcomes in T2D remains unclear. This study investigates the associations of (1) ADHD and (2) ADHD medication use with rates of major adv...

Zi-Han Dong, Yi-Ling Zhou, Hong-Hui Yao et al. · 0 citations
Aug 2026

Antipsychotic medication and the prevention of psychiatric emergencies in difficult-to-treat adolescent depression.

OBJECTIVES It is unclear how antipsychotic medications affect acute healthcare use among adolescents with depression. We compared risk of psychiatric emergencies between adolescents with difficult-to-treat depression initiating new antipsychotic versus antidepressant medications. METHODS This cohort study employed a...

Linnea Sepe-Forrest, Richard Meraz, Zheng Chang et al. · 0 citations
Open access Sep 2026

Lifetime substance use disorder and suicidal behaviour: a population-based familial co-aggregation register study.

Substance use disorders (SUD) are associated with suicidal behaviour, but less is known regarding the extent to which familial factors influence these associations across different types of SUD. We performed a national register study including 4,209,615 individuals born in Sweden 1958-1999 and followed 1973-2020. Expos...

L. Khemiri, R. Kuja-Halkola, Henrik Larsson et al. · 0 citations
Open access Jul 2026

Shared Genetic Factors Between Stress-related Disorders and Cardiovascular Disease.

A genetic comorbidity framework in which shared genetic liability, largely driven by pleiotropic loci, contributes to the co-occurrence of SRDs and CVD is supported and candidate genes and biological processes for future experimental studies are highlighted.

C. Hou, Yu Zeng, Hua-Zhen Yang et al. · 0 citations
Open access Aug 2026

Real-world ADHD pharmacological treatment patterns and their association with negative clinical outcomes in youth with comorbid autism: a Swedish population-based study

The findings suggest that, rather than recommending fixed first-line and second-line treatments for individuals with ADHD-ASD, clinical guidelines should emphasise appropriate training as well as prompt and individualised treatment based on a shared decision-making process.

M. Garcia-Argibay, R. Kuja-Halkola, B. D'Onofrio et al. · 0 citations

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