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B. D. Murphy

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Sep 2026

Nodal/Smad2 signaling maintains diapause in the mouse embryo.

Embryonic diapause is a reversible dormant state that allows mammalian blastocysts to survive periods of environmental or metabolic stress. In this issue of Developmental Cell, Furlan et al.1 report that Nodal/Smad2 signaling sustains diapause by repressing Pparg-driven lipid storage in the blastocyst.

B. D. Murphy · 0 citations

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