Author

B. Clark

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Open access Oct 2026

High-throughput serial two-photon tomography with BakingTray and BrainSaw

Volumetric imaging is increasingly important in fields such as neuroscience, where quantifying structure and mapping features are inherently three-dimensional problems. Block-face serial two-photon tomography (STPT) has emerged as a powerful approach for high-resolution, whole-organ volumetric imaging. STPT avoids comp...

R. Campbell, Kurt I. Anderson, A. Ayaz et al. · bioRxiv · 0 citations

Open access Sep 2026

Exponentiated gradient learning yields brain-like synaptic distributions.

Artificial neural networks trained with gradient descent (GD) are widely used to model brain learning, but GD allows synapses to switch between excitatory and inhibitory and produces weight distributions unlike those observed experimentally. We show that an alternative rule, exponentiated gradient (EG), avoids these pr...

Jonathan Cornford, Roman Pogodin, Arna Ghosh et al. · Neuron · 0 citations