Therapeutic vaccination strategy targeting the PreS1 region of L-HBsAg for HBV/HDV co-infection.
BACKGROUND & AIMS Achieving functional cure for chronic hepatitis B (CHB) will likely require a combinatorial approach targeting multiple aspects of the complex hepatitis B virus (HBV) life cycle and host adaptive immune responses. Here, we developed a therapeutic vaccination strategy targeting the PreS1 region of L-HB...