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Author

B. Barzon

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Open access Aug 2026

Melatonin system integrity shapes gut-brain interaction in schizophrenia-derived microbiota transplant phenotype in mice.

AIMS This study investigates whether the melatonin (MLT) system modulates the behavioral, neurophysiological and neurochemical effects of fecal microbiota transplantation (FMT) from individuals with schizophrenia (SCZ), highlighting the role of the tryptophan (Trp) to MLT and kynurenine (Kyn) pathways. MATERIALS AND...

B. Barzon, A. Shkodra, M. D'Incalci et al. · 0 citations
Open access Sep 2026

310. Melatonin MT2 receptors activation attenuates MK-801-induced schizophrenia-like effects

Abstract Background Schizophrenia (SCZ) is a chronic psychiatric disorder characterized by positive, negative, and cognitive symptoms that remain insufficiently addressed by existing dopamine- and serotonin-based antipsychotics. Emerging evidence implicates melatonin MT2 receptors in the regulation of circadian rhythms...

B. Barzon, F. Marchiotto, S. Nasini et al. · 0 citations
Open access Sep 2026

668. Serotonin, melatonin, and kynurenines: bridging neurochemical pathways in schizophrenia and beyond

Investigating the interplay between Trp metabolism, inflammation, and gut microbiota in modulating cognitive and metabolic phenotypes in schizophrenia suggests that dysregulated Trp metabolism acts as a translational bridge connecting genetic background, metabolic status, and microbiota-derived signals to SCZ pathophys...

B. Barzon, A. Shkodra, S. Nasini et al. · 0 citations

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