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Review Open access Oct 2026

Harnessing the ubiquitin-proteasome system: advances and challenges of PROTACs in breast cancer

Breast cancer is one of the most significant health issues in the world, and resistance to treatment and a lack of targets that can be addressed with drugs limit the effectiveness of the existing treatment options. The development of proteolysis-targeting chimeras (PROTACs) has shifted the concept of occupancy-based in...

Hannah Lalengzuali Fanai, B. Babu, K. Rajagopal et al. · 0 citations

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