Background: Breast cancer (BC) progression depends on immune dysregulation and complex interactions between tumor cells and host immune components. Soluble immune checkpoints, growth factors, chemokines, and cytokines are promising circulating biomarkers; however, their clinical relevance across IHC-defined clinicopath...
Rania Zaki, Auhood Nassar, R. A. Al Najar et al.· Cells· 0 citations
Folate-functionalized chitosan nano-formulations significantly enhanced the anticancer efficacy of quercetin and Coriandrum sativum seed extract through improved targeted delivery, potent antiproliferative, anti-angiogenic, and pro-apoptotic activities, together with favorable modulation of multiple molecular pathways...
Nariman Nabil, Hussein Sabit, J. Almulhim et al.· Pharmaceuticals· 0 citations
Overall, epigenetic plasticity represents both a major driver of TNBC resistance and a therapeutically exploitable vulnerability, provided those future strategies account for tumor heterogeneity, adaptive cell-state transitions, biomarker-guided patient selection, and combination-based treatment design.
A. Alaa, Salma A. B. El-Din, Mohannad A. Farrag et al.· Biomedicines· 0 citations
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