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Author

B. A. Abdrazik

2 papers indexed here

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Open access Sep 2026

Molecular docking, dynamics, and ADME studies of new isatin derivatives as histone deacetylase (HDAC) inhibitors

Histone deacetylase-2 (HDAC-2) is an important therapeutic target in cancer treatment. Isatin derivatives have attracted considerable interest in medicinal chemistry because of their diverse biological activities. The present study aimed to investigate a series of newly designed isatin derivatives as HDAC-2 inhibitors...

Hanan Adil Salih, Rafid M. Hashim, B. A. Abdrazik et al. · 0 citations
Open access Sep 2026

Design and In Silico Evaluation of Novel 1,3,4-Oxadiazole Derivatives as Potential CYP51B Inhibitors Against Aspergillus fumigatus

Antifungal resistance and invasive fungal infections remain the major therapeutic issues, especially in patients with impaired immune systems. Aspergillus fumigatus is the main cause of invasive aspergillosis and sterol 14-α-demethylase (CYP51B), a key enzyme in the biosynthetic pathway of ergosterol, is an important t...

Shams Khaleel Ibraheem, B. A. Abdrazik, H. Alsaad et al. · 0 citations

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