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Author

Aziz Kubaev

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Review Open access Aug 2026

Epigenetic Rewiring and Context‐Dependent Therapeutic Vulnerabilities in Myeloproliferative Neoplasms

Myeloproliferative neoplasms (MPN) are shaped by epigenetic rewiring that extends beyond canonical JAK2V617F‐driven signaling. This review argues that context‐dependent chromatin states, not merely genetic lesions, determine disease trajectory, fibrotic transformation, and leukemic progression. We synthesize recent evi...

Amr Ali Mohamed Abdelgawwad El-Sehrawy, M. Al-Khreisat, Aziz Kubaev et al. · 0 citations
Review Open access Sep 2026

Convergent evolution of immune evasion in ESKAPE pathogens: A cross-pathogen architecture of conserved host-defense checkpoints

Abstract Antimicrobial resistance in ESKAPE pathogens is primarily attributed to resistance genes, yet persistent infections despite appropriate therapy implicate immune evasion as an independent driver of treatment failure. Although immune-evasion mechanisms have been extensively characterized in individual pathogens,...

U. Nabieva, Dilorom Abdusamatova, Aziz Kubaev et al. · 0 citations

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