Podocyte Biology in Pediatric Glomerular Disease: From Slit Diaphragm Assembly to Genotype-Guided Therapy—A Narrative Review
The podocyte is a terminally differentiated cell whose foot processes and slit diaphragm form the final layer of the glomerular filtration barrier. Because podocytes are not effectively replaced after birth, and nephron number is fixed before it, their cumulative loss converts congenital and steroid-resistant nephrotic...