Open access
Sep 2026
A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering
The work successfully shows robust mRNA expression, functional CFTR activity in vitro, and appropriate in vivo tissue localization, and further validation is needed—specifically physiological assessments such as nasal potential difference and mucus clearance measurements—before advancing to clinical trials.
Neha Kaushal, You-Nan Ma, A. Khanmohammed et al.
· Advanced Functional Material... · 0 citations