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Author

Aylin del Moral-Morales

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Review Open access Aug 2026

Advances in the emerging field of epi-informatics in drug discovery: roads taken and future prospects.

An updated overview of bioinformatics, chemoinformatics, and machine learning methodologies used to identify, design, and optimize compounds that modulate epigenetic processes with therapeutic potential and examines the epigenetic drug discovery landscape by analyzing the most extensively investigated epigenetic target...

Aylin del Moral-Morales, Erik D. Díaz-Dionisio, Josė L. Medina-Franco · 0 citations
#protein folding Open access Aug 2026

Ser715 Phosphorylation Induces β-Hairpin Unfolding and Destabilization of FOXM1 Autoinhibition.

A phosphorylation-triggered order-to-disorder transition that relieves FOXM1 autoinhibition and highlight Ser715 as a key structural and energetic switch is supported and provided a dynamic molecular framework for targeting FOXM1 activation via its regulatory fold.

Sara AlRawashdeh, Raghd Obidat, Aylin del Moral-Morales et al. · 1 citation

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