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Author

Aydın Genç

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Open access Sep 2026

Apilarnil Mitigates Copper Nanoparticle-Induced Hepatorenal Injury in Rats: Associations with Oxidative Stress, Inflammatory Markers and ER-Stress-Related Gene Expression

Background/Objectives: This study investigated the preventive effects of apilarnil (APL) against copper nanoparticle (CuNPs)-induced liver and kidney injury in rats. Methods: Thirty-five rats were randomly allocated into five groups (n = 7): Control (physiological saline), APL (400 mg/kg), CuNPs (100 mg/kg), CuNPs + AP...

Aydın Genç, Sefa Kucukler, F. M. Kandemir et al. · 0 citations
Open access Sep 2026

Modulatory Role of Vitamin E on Oxidative Stress, Inflammation, and Autophagy in Oxytetracycline Induced Renal Toxicity

Vitamin E exerts a protective effect against OTC-induced renal injury by attenuating oxidative stress and modulating inflammation and autophagy pathways, highlighting its potential as a supportive therapeutic strategy against antibiotic-induced nephrotoxicity.

Aydın Genç, F. M. Kandemir, E. Dalkılınç et al. · 0 citations
Open access Aug 2026

Ameliorative Role of Selenium in Enrofloxacin-Induced Liver Damage: An Experimental Rat Study

SE was found to exert hepatoprotective effects against ENRO induced liver injury by reducing lipid peroxidation, strengthening antioxidant defense systems, and regulating inflammatory and autophagic responses.

Aydın Genç, F. M. Kandemir, E. Dalkılınç et al. · 0 citations

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