Author

Axel Sandvig

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Open access Sep 2026

Ion modulation restores local synaptic function in APOE4 neuronal networks despite persistent impairments in global network organization

It is shown that APOE4 networks retain a capacity for adaptive plasticity enabling restoration of local neuronal function, but that this recovery does not extend to higher-order network organization.

Marthe Bendiksvoll Grønlie, Anna Mikalsen Kollstrøm, Axel Sandvig et al. · bioRxiv · 0 citations