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Avner Thaler

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Open access Oct 2026

Blood-brain barrier dysfunction and altered choroid plexus contrast kinetics in Parkinson’s disease

Neurovascular dysfunction may contribute to Parkinson’s disease (PD), but the extent and clinical relevance of blood-brain barrier alterations remain uncertain. We investigated regional blood-brain barrier permeability, fractional plasma volume, and choroid plexus contrast kinetics in patients with PD using dynam...

Sapir Fajerzstein, Gadi Maayan Eshed, Sheida Mirloo et al. · 0 citations
Open access Sep 2026

The Effect of LRRK2 and GBA1 Mutations on Survival in Early- and Late-Onset Parkinson's Disease.

BACKGROUND Mutations in the glucocerebrosidase 1 (GBA1) and leucine-rich repeat kinase 2 (LRRK2) genes are associated with Parkinson's disease (PD) phenotype. OBJECTIVE To asses the contribution of genetic status to long-term survival of patients with PD. METHODS A total of 2039 PD patients with Ashkenazi ancestry...

Raz Rubin, R. Alcalay, Nurit Omer et al. · 0 citations

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