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Author

Audronė Rukšėnaitė

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2 papers indexed here

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Open access Oct 2026

Csx15 is a broad specificity ring nuclease bridging CRISPR-Cas and CBASS cyclic nucleotide signaling systems

Prokaryotic antiviral type III CRISPR-Cas and CBASS systems use cyclic nucleotides as second messengers to activate diverse effector proteins. Whereas CBASS signaling typically triggers abortive infection, type III CRISPR-Cas signaling is tightly regulated through controlled signal production and degradation. Here, we...

D. Klimavicius, Dominik Rafalski, Dalia Smalakytė et al. · 0 citations
Open access Sep 2026

Live-cell DNMT3A “catalysome” mapping using engineered methyl-transfer pathways

Abstract Catalytic interplay among three major DNA methyltransferases (DNMTs) establishes and maintains genomic modification patterns that define mammalian cell identity and transitions during development. Despite extensive molecular characterization, mechanisms and precise contributions of DNMT-specific methylation in...

V. Stankevičius, Liepa Gasiulė, Kotryna Kvederavičiu̅tė et al. · 0 citations

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