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Author

Atousa Bahrami

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2 papers indexed here

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Open access Sep 2026

α-Synuclein Seeding in Dopaminergic Neurons Transplanted into the Putamen of Parkinson’s Disease Patients

Healthy embryonic neurons grafted into the putamen of Parkinson’s disease (PD) patients start to develop Lewy pathology 10 years after transplantation. It remains unclear whether this pathology is initiated by the spread of host-derived α-synuclein (αsyn) aggregates which seed aggregation in the grafted cells or arises...

Jayda B. Duvernay, B. Killinger, Solji G. Choi et al. · 0 citations
Open access Jul 2026

Preformed Fibril Seeding Reshapes the Phosphorylated α-Synuclein Proximal Proteome in the Olfactory Bulb

In both models, the CIAP-resistant interactome largely overlapped with the broader PS129 interactome, suggesting that seeded aggregation primarily affects existing PS129 interactions rather than directing the formation of new pathological ones.

Solji G. Choi, Atousa Bahrami, Jayda B. Duvernay et al. · 1 citation

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