Atharv Chandra

Multi-omic spatial mapping of the human habenula defines the molecular and anatomical organization of medial and lateral subregions

The habenula (Hb) is a small epithalamic midline structure critical for reward processing and mood regulation that is implicated in many complex brain disorders, including depression and addiction. The molecular anatomy of the Hb has been well-characterized in model organisms, but little is known about its organization...

Molecular programs in human locus coeruleus link APOE and neuromelanin to Alzheimer’s vulnerability