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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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Astar Shamul-Raybi

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Open access Sep 2026

Computational design of optimized and preferentially paired human TCR constant regions for improved T cell function

T cell receptor (TCR) gene transfer is a promising approach for cancer immunotherapy, but its efficacy is limited by mispairing of TCR chains, which reduces surface expression and may generate off-target specificities. We applied the PROSS and FuncLib algorithms to engineer human TCR constant regions for improved stabi...

Maria Radman, Astar Shamul-Raybi, Jake Parker et al. · 0 citations

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