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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Ashok Sekhar

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Open access Aug 2026

Morpheus-3D: Structural Diversity-Guided Detection and Localization of Protein Fold Switching

Morpheus-3D is presented, a sequence-based framework that quantifies residue-level tertiary structural diversity using entropy profiles derived from the Foldseek 3Di structural alphabet and provides a scalable framework for discovering metamorphic proteins and investigating the origins, mechanisms, and evolution of str...

Sreeharsh Kuniyil, Vijay Subramanian, Akanksha Arun et al. · 0 citations

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