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Asako Kakimoto

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Open access Sep 2026

Detection of α-synuclein seeding activity in tear fluid as a candidate biomarker for Parkinson's disease

Background Parkinson's disease (PD) is an α-synucleinopathy, and pathological α-synuclein (α-Syn) is detectable in peripheral tissues and fluids. However, the diagnostic utility of tear fluid as a minimally invasive source for α-Syn seed detection remains unclear. We aimed to detect α-Syn seeds in tear fluid and evalua...

Asako Kakimoto, K. Satoh, Tomoko Tsukahara-Kawamura et al. · 0 citations

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