Arya Bhakare

Release of the Staphylococcus aureus autoinducing peptide is enabled by active export of the biosynthetic intermediate

Staphylococcus aureus is a species of Gram-positive bacteria that uses the accessory gene regulator (agr) quorum sensing system to regulate many aspects of cell behavior such as virulence and toxin production. Quorum sensing is activated in dense S. aureus populations by the extracellular accumulation of a signaling mo...