Association of the G/G Genotype with Insulin Resistance, Dyslipidemia, And Hyperleptinemia
Background. Obesity is a multifactorial disease arising from interactions among environmental, behavioural, metabolic, and genetic factors. The leptin signalling system is a key component of the central regulation of energy balance. The rs1137100 polymorphism of the leptin receptor gene (LEPR) results in the Lys109Arg...