Arnab Mukherjee

Protein Breathing Induces Non-Markovian Buried Ring-Flip Dynamics in Cytochrome C

Aromatic amino acids buried inside folded proteins play a critical role in stabilizing both the folded conformation and anchoring incoming substrate molecules. Moreover, their ring flips serve as sensitive probes of protein breathing motions. In this work, we accurately estimate the ring-flip rates of a phenylalanine...