A Competing C-Terminal β-Turn Controls Frame-Dependent Stability of Collagen Triple Helices
Frame-dependent stability of collagen triple helices is well documented, but its structural origin remained unresolved. Here we identify a C-terminal β-turn-like conformational state with intramolecular CO···HN contacts as the competing motif governing this behavior. In POG-frame collagen mimetic peptides, a C-termin...