Diabetes mellitus (DM) remains a global metabolic disorder characterized by chronic hyperglycemia and progressive microvascular and macrovascular complications. Although plant-derived bioactive compounds have demonstrated promising antidiabetic properties including insulin sensitization, β-cell protection, α-glucosidas...
Arionget Jemima· IDOSR Journal of Scientific...· 0 citations
Oxidative stress is a central molecular mechanism underlying diverse pathological conditions. It results from an imbalance between pro-oxidant species and antioxidant defenses, leading to widespread molecular damage via lipid peroxidation, protein oxidation, DNA damage, and perturbation of redox homeostasis. This revie...
Arionget Jemima· IDOSR Journal of Applied Sci...· 0 citations
Accumulating data indicated that mRNA platforms permitted precise encoding of stabilized envelope trimers, germline targeting constructs, and mosaic immunogens, resulting in improved antigen expression and enhanced induction of neutralizing antibody precursors in animal models and early human trials.
Arionget Jemima· IDOSR Journal of Scientific...· 0 citations
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