Review
Open access
Aug 2026
Pharmacogenetic Predictors of Chemotherapy Treatment-Related Toxicities in Paediatric and Adolescent Acute Lymphoblastic Leukemia: A Systematic Review, Meta-Analysis and Literature-Based Candidate Prioritization
The review supports routine TPMT and NUDT15 genotyping and highlights the need for harmonised definitions, multi-ethnic studies, standardised data representation, and prospective validation of identified variants, which remains to be evaluated prospectively.
Santenna Chenchula, S. Srinivasamurthy, Vinnyfred Vincent et al.
· Pharmaceuticals · 0 citations