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Archanalakshmi Kambaru

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Jul 2026

Apo and substrate-bound dihydropteroate synthase crystal structures from Thermus thermophilus HB8.

High-resolution crystal structures of Thermus thermophilus HB8 DHPS and homologs from Escherichia coli and Mycobacterium tuberculosis highlight conserved catalytic features, as well as variable loop conformations and phosphate-binding residues that may contribute to differential sulfonamide sensitivity.

Amulya Ramakrishna, Archanalakshmi Kambaru, K. Gokulakrishnan et al. · 0 citations

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