Pathways of early evolution from the perspectives of a riboreplisome -- the ultimate RNA machine of life
It is proposed that early replication and protein biosynthesis were inseparable functions performed by a single ancient RNA molecule: the riboreplisome, and this hypothesis addresses fundamental challenges facing RNA world, protein world, and RNA-protein co-evolution theories.
Alice Cleynen, Archa H. Fox, Nikolay E. Shirokikh
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