Review
Open access
Oct 2026
DYRK1A – a gene dose paradox
The DYRK1A (Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A) gene is located on human chromosome 21 (HSA21) within the Down Syndrome Critical Region (DSCR). As a protein kinase, DYRK1A is involved in the regulation of the cell cycle, cell growth, transcription, and cellular communication. It also pl...
A. Plećaš, Gillian Gough, Sandra Kunštek et al.
· Frontiers in Cell and Develo... · 0 citations