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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Antonio Ramkissoon

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Sep 2026

A Platform for the Production of Pleuromutilin and Core-Modified Derivatives

The structural complexity of pleuromutilin antibiotics has limited efforts to define aspects of the natural scaffold that are required for antibacterial activity. Here, we present a scalable synthetic platform that provides access to novel core-modified bicyclic pleuromutilins (BPs) and the natural tricyclic pleuromu...

Zhan-Hao Liang, Q. Yang, Antonio Ramkissoon et al. · 0 citations

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