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Author

Antonio Costanzo

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Jul 2026

Psoriasis-risk SNP rs610604 reveals nuclear IKKα-TNFAIP3 repressor axis driving autoinflammatory circuits.

A nuclear IKKα-TNFAIP3 axis linking genetic susceptibility to inflammatory signaling is identified, providing a potential explanation for the paradox of chronic inflammation without frequent malignant transformation in psoriatic skin, and highlighting IKKα as a potential therapeutic target in psoriasis and related infl...

Maria Benedetta Rizzarda Maffezzoni, F. Moretti, E. Botti et al. · 0 citations

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