Antonio Armario

Impact of previous acute and chronic stress on negative glucocorticoid feedback in laboratory animal: theoretical background and methodological concerns.

Chronic stress or acute severe stressors have been extensively used as putative animal models of psychiatric diseases, particularly depression and post-traumatic stress disorder (PTSD), respectively. The hypothalamus-pituitary-adrenal (HPA) axis not only represents a prototypical stress response system, but also mediat...