Amyloid-β plaque diversity across brain regions in Alzheimer’s disease and its relation to major clinicopathological traits
Amyloid beta (Aβ) deposition and tau accumulation are neuropathological hallmarks of Alzheimer’s disease (AD). While Aβ deposits present with a wide morphological variety, a comprehensive, cross-regional overview of Aβ plaque composition in AD and associations with clinicopathological traits are missing. In this study,...