Author

Anton Kan

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Open access Sep 2026

Biosurfactants direct the evolutionary dynamics of surface-associated microbial systems

Surface-associated microbial systems experience spatial constraints that can intensify stochastic lineage loss through genetic drift and alter how natural selection acts on competing lineages. A key feature of these systems is that steep resource gradients typically confine growth to a narrow band of cells located at t...

Chu-Jin Ruan, Bi-Jing Xiong, Deepthi P. Vinod et al. · Science Advances · 0 citations

Open access Aug 2026

Directed Evolution of an Escherichia coli Secretor Strain Using the Curli Pathway

This work developed a Green Fluorescent Protein (GFP) secretion system by fusing GFP of the N-terminus sequence from the curli monomer protein while co-expressing the curli export machinery and found that secretion was sequence-specific, although no simple metric could predict success.

Anton Kan, S. Emani, Neel S. Joshi · ACS Synthetic Biology · 0 citations