Open access
Jul 2026
Essentiality-driven prediction of anticancer drug responses in preclinical and clinical contexts
DrGee is presented, an essentiality-centered platform that infers drug sensitivity solely from gene expression profiles, and the built-in DeepEEAA model integrates gene expression, gene essentiality, drug-protein affinity, and drug-gene associations to quantitatively predict IC50 values.
Hongtu Cui, Xiaohui Du, Hai-Xia Guo et al.
· iScience · 0 citations