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Author

Anneliese M. Faustino

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Aug 2026

Global Incorporation of a Photo-Cross-Linking Amino Acid to Probe the Protein Interactome under Physiological Conditions.

Proteome-wide incorporation of DizPK, a diazirine-containing lysine analog with a dedicated MS-cleavable urea functionality, is demonstrated via stochastic orthogonal recoding of translation and subsequent identification of photo-cross-linked peptides to map protein-protein interactions under physiological conditions.

Piyoosh Sharma, Divya Yadav, Anneliese M. Faustino et al. · 0 citations

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