Open access
Jul 2026
The linker histone H1.4 condenses chromatin in maturing postmitotic neurons
The expression of H1f4 mRNA and H1.4 protein in the brains of male and female mice across postnatal development is characterized and it is shown that developmental maturation of chromatin compaction in cerebellar granule neurons is disrupted in H1f2/H1f4 double knockout mice.
Andrew I. Aldridge, Martine W. Tremblay, Vijyendra Ramesh et al.
· bioRxiv · 0 citations