The state of the art in RNA structure prediction is reviewed, covering key training datasets, community benchmarks, and the performance of current models, as well as perspectives on integrating other data modalities, such as chemical probing signals and RNA modifications, as well as the emerging role of generative models.
Lambert Moyon, Annalisa Marsico· Current Opinion in Structura...· 0 citations
Parnet is a multi-task foundation model trained end-to-end on 223 eCLIP-seq experiments spanning 150 RBPs to predict base-resolution RBP binding profiles directly from RNA sequence, and establishes the RBP interactome as a compact, functionally sufficient, and interpretable basis for foundation model pretraining in RNA biology.