Background/Objectives: Inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), show substantial variability in response to biologic therapies. Ustekinumab, which targets the IL-12/23 pathway, is an established treatment for moderate-to-severe IBD; however, a proportion of patients...
Ylenia Marino, M. Rottura, Claudia Ligresti et al.· Pharmaceuticals· 0 citations
DLSCT showed high concordance with MRI for several locoregional imaging features of rectal cancer, and may provide complementary information, particularly when MRI is contraindicated or inconclusive, but these findings do not establish equivalence to MRI or diagnostic accuracy against histopathology.
S. Mazziotti, Giorgio Ascenti, Tommaso D'Angelo et al.· Diagnostics· 0 citations
BACKGROUND AND AIMS
Upadacitinib is an oral selective JAK1 inhibitor approved for moderate-to-severe Crohn's disease (CD), but real-world prospective multicentre data in advanced therapy-experienced (AT-experienced) patients are limited. The UPGRADE-CD study evaluated its effectiveness and safety.
METHODS
In this pro...
B. Barberio, F. D'Amico, L. Laterza et al.· Alimentary Pharmacology and...· 0 citations
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