Anna R. Barth

Shear Strain Stiffening in Cartilage is Governed by a Mechanical Phase Transition

Large shear deformation in cartilage can lead to tissue failure and injury, which are often precursors to diseases such as post-traumatic osteoarthritis. Under shear, cartilage strain-stiffens prior to failure, which makes stiffening an important indicator of changes to the loading of the extracellular matrix that give...