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Anna Lisa Heit

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Open access Aug 2026

Intra-Protein Interfaces Control Folding Dynamics and Mechanical Stability in a De Novo Designed Repeat Protein

Together, these results show that designed repeat-protein folding is governed by seed formation, interface propagation, and terminal boundary conditions, and establish intramolecular crosslinking as a strategy for rationally reshaping folding landscapes in designed proteins.

Melanie Weiß, Anna Lisa Heit, L. Milles et al. · 0 citations

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