De novo design of light-controlled conformational protein switches
Light-responsive proteins offer the ability to control biology at an unmatched resolution. Yet, optogenetics is limited to a relatively small number of natural and engineered photoreceptors. The design of light-responsive proteins with native-like complexity is challenging as they must incorporate a light-responsive ch...
Alexander T. Hilditch, N. Goldbach, Chen-Xuan Liu et al.
· bioRxiv · 0 citations