Accurate and precise quantification of trace-level cytokines in complex biological matrices remains challenging, limiting their use as longitudinal biomarkers in clinical studies. Here, we present a nanotechnology-enabled surface-enhanced Raman scattering (SERS) platform incorporating an internal standard (IS) for di...
Yi-Wen Zhang, Fahimeh Farokhinejad, Jacob J. Crouse et al.· Analytical Chemistry· 0 citations
Advances in sequencing technologies have transformed human genetics and accelerated disease gene discovery. Yet a causal mutation remains to be identified for many families with an inherited disease. Incomplete penetrance, genetic heterogeneity, and limited family history can complicate the binary classification of fam...
L. Henden, Sandrine Chan Moi Fat, Andrew N. Smith et al.· Brain : a journal of neurolo...· 0 citations
Internalising symptoms including depression, anxiety and somatic symptoms in adolescence are common. They can be transient, but they can also persist and progress to major depressive disorder (MDD) Polygenic risk scores for major depression (MD-PGS) may help identify which symptomatic adolescents are at greatest risk o...
E. Byrne, Nathan A. Gillespie, J. Najman et al.· Molecular Psychiatry· 0 citations
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