Anirudh Lahiri

Genome-guided discovery of clavaic acid, a decalin-containing polyketide encoded by a LovB-like polyketide synthase

Functional analysis of the condensation domain in vivo demonstrated that it is essential for clavaic acid biosynthesis, and expands the understanding of LovB-like iPKSs and establishes this enzyme family as a promising source of cryptic fungal polyketides.