Author

Angélica Leticia Barraza-Arellano

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Open access Oct 2026

Mitochondrial respiratory complexes, excitation-contraction coupling and mTOR signaling transcriptional programs are dysregulated in cardiometabolic HFpEF

Heart failure is a leading cause of death and disability worldwide. Nearly, half of the cases correspond to HF with preserved ejection fraction (HFpEF), which is predicted to become the most prevalent form of HF in the forthcoming years. In this study, we performed a bulk RNA-seq assay to study the transcriptomic profi...

Abraham Méndez-Fernández, Angélica Leticia Barraza-Arellano, Víctor Treviño et al. · bioRxiv · 0 citations

Open access Aug 2026

Performance of PREMM5, clinical criteria, and immunohistochemistry for MMR proteins in genetic risk assessment of Mexican patients with colorectal cancer

Considering the spectrum of PVs identified, employing a multigene panel test is recommended for Mexican patients with CRC, and the performance of PREMM5 in this Mexican cohort was comparable to findings reported in validation studies within other populations.

J. L. Rodríguez-Olivares, D. Aguilar-y-Mendez, Tamara N. Kimball et al. · PLoS ONE · 0 citations