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Author

Angela Risch

2 papers indexed here

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Open access Oct 2026

Large-scale association study identifies lung cancer susceptibility copy number variants and their potential functional role in genetic instability.

BACKGROUND Genome-wide association studies (GWAS) have identified numerous lung cancer susceptibility loci based on single nucleotide polymorphisms (SNPs), yet a substantial proportion of heritability remains unexplained. We therefore evaluated germline copy number variants (CNVs) as an underexplored source of genetic...

Fei-Fei Xiao, Fei Qin, Xi-Zhi Luo et al. · 0 citations
Open access Aug 2026

G-quadruplex structures act as a novel recognition motif for the meiosis-specific histone methyltransferase PRDM9

A model in which stable G4 structures facilitate PRDM9 recruitment by creating and discrete increased local chromatin accessibility, thereby contributing to the initiation of meiotic recombination is supported.

Mia K. Hartge, Nuria Pfennig Hernández, Tomáš Pavlík et al. · 0 citations

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