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Aneta Grycová

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#protein folding Open access Oct 2026

In vitro pharmacological profiling of ITE amide bioisosteric aryl hydrocarbon receptor agonist

Previously, we reported ITE-derived bioisostere 2-(1 H -indole-3-carbonyl)-N-methyl thiazole-4-carboxamide (ITE-CONHCH 3 ) as a high-affinity ligand and potent agonist of the aryl hydrocarbon receptor (AhR) with anti-colitis properties. In the current study, we present its initial in vitro pharmacological profi...

Zdeněk Dvořák, Aneta Grycová, R. Vrzal et al. · 0 citations

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