PURPOSE
The Soma and Neurite Density Imaging (SANDI) model enables characterization of gray matter (GM) microstructure by estimating soma and neurite signal fractions, but its clinical applicability is limited by the need for multi-shell acquisitions (at least five b-values up to 6000 s/mm2), requiring high-gradient MR...
Hansol Lee, Kwok-Shing Chan, Yixin Ma et al.· Magnetic Resonance in Medici...· 0 citations
MRI continues to be the foundation of multiple sclerosis (MS) diagnosis and management. The latest innovations in technology have paved the way for earlier diagnosis, more informed treatment selection, better means of evaluating the disease course, and personalized therapeutic responses. This review summarizes the most...
N. Michaelson, Sittaya Buathong, C. Treaba et al.· Radiology· 0 citations
BACKGROUND AND PURPOSE
Neurodegeneration is a key component of clinical disability in multiple sclerosis (MS). However, the underlying mechanism of localized gray matter (GM) atrophy in MS remains unknown. More recently, a network-based etiology has been postulated, which may be associated with clinical progression. Th...
Florence L. Chiang, Eva A. Krijnen, Diana A. Hobbs et al.· AJNR. American journal of ne...· 0 citations
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